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I have used it quite a few times. For performance, WineASIO would need to be installed and registered in the wineprefix for this install. Other than that, it runs great:

#!/bin/bash
# Date : (2013-02-01)
# Last revision : (2013-02-01)
# Distribution used to test : Kubuntu 12.04 LTS
# Author : DJYoshaBYD
# Licence : GPLv3
# PlayOnLinux: 4.1.9
  
  
[ "$PLAYONLINUX" = "" ] && exit 0
source "$PLAYONLINUX/lib/sources"
  
PREFIX="GuitarRig5"
WINEVERSION="1.5.20"
TITLE="Guitar Rig 5"
  
#Initialization
POL_SetupWindow_Init
  
POL_Debug_Init
  
# Presentation
POL_SetupWindow_presentation "$TITLE" "Native Instruments" "http://www.native-instruments.com" "DJYoshaBYD" "$PREFIX"
  
# Create Prefix
POL_System_SetArch "x86"
POL_Wine_SelectPrefix "$PREFIX"
POL_Wine_PrefixCreate "$WINEVERSION"
  
#Dependencies
  
# Configuration
Set_OS "winxp"
POL_Wine_Direct3D "DirectDrawRenderer" "gdi"
  
# Installation
POL_SetupWindow_browse "$(eval_gettext 'Please select $TITLE install file. During installation, uncheck all extra drivers it wants to install:')" "$TITLE"
POL_Wine_WaitBefore "$TITLE"
GC_DONT_GC=1 POL_Wine "$APP_ANSWER"
POL_Wine_WaitExit "$TITLE"
  
# Create Shortcuts
POL_Shortcut "Guitar\\ Rig\\ 5.exe" "$TITLE"
  
POL_SetupWindow_message "$(eval_gettext 'NOTICE: For low-latency audio, look into WineASIO.')" "$TITLE"
 
POL_SetupWindow_Closeexit 0

Edited by RoninDusette

Screenshots:

Don't forget to end your scripts in "exit 0".
PlayOnLinux appends a digital signature at the end of scripts, so this is a requirement to avoid weird errors with Bash trying to interpret gpg signature ;)

Whoops. I actually did have it on there. Must have gotten cut off when cut&pasting. sorry aboot that. I actually have like, 5 more scripts related to just music software that Im going to do over the weekend. lol.

Petch: 

hey buddy i`m noob can you help to use your script , i want to test guitar rig on my ubuntu and i have no ideia how to, other thing i look some topics on the internet some guys using wineasio to run it, is it necessary tks...

Edited by morpheusmat

You will need to read the wiki so that you know how to use PlayOnLinux to install this program, and then you will need to install WineASIO into that virtual drive from Install Components tab. It is not needed unless you want low-latency audio so that when you hit a string, it is processed and played with little delay.