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All versions of photoshop do run and have received confirmation from the wine community however I believe many are installing the "32bit" versions of the program not 64-bit. 

I have licenses for CS4, CS5, and CS6 Master Suites and would like to install cs5 or cs6 64-bit onto my linux box.

I'm running Debian Testing(Wheezy).

Here's my specs if it helps.

Case: Silverstone Fortress FT02B-W
CPU: i7 3820 Sandy Bridge-E LGA 2011
GPU: Galaxy: Nvidia Geforce GTX 680,
Mobo: Asrock X79 Extreme9 w' creative sound
RAM: 2X Patriot 2 8GB DDR3 1600MHZ (64GB max)
SSD: Muchkin 128GB, HDD: Western Digital 1TB Green
PSU: Rosewill Lightning 1000W

So obviously I'm runing an amd64(x86_64) system but many packages such as msxml6, vcrun2005 just do not work on 64bit systems.

Help please.

Edited by Rukiri

I think then what you want to run is wine64:
http://wiki.winehq.org/Wine64

I am having the same problem, now I will give up trying to install ps cs5,

ps. I tried with wine in both 32b and 64b could not